The LC Detector Selector is a scientifically grounded decision tool designed for analytical chemists, method development scientists, and laboratory professionals working in HPLC, UHPLC, and LC-MS environments.

Selecting the correct LC detector is critical for sensitivity, selectivity, robustness, and regulatory compliance. This interactive tool evaluates analyte properties such as chromophore presence, fluorescence potential, ionic character, polarity, volatility, redox activity, and expected concentration range.

Based on these inputs, the simulator recommends the most appropriate detection method among:

UV–Visible detection

Photodiode Array (PDA/DAD)

Fluorescence detection (FLD)

Refractive Index (RID)

Charged Aerosol Detection (CAD)

Evaporative Light Scattering Detection (ELSD)

Electrochemical detection (ECD)

LC-Mass Spectrometry (LC-MS)

The tool also considers mobile phase composition, gradient vs isocratic conditions, buffer compatibility, and matrix complexity to provide chemically accurate, method-relevant recommendations.

Ideal for:

HPLC method development

UHPLC troubleshooting

LC-MS method planning

Pharmaceutical analysis

Environmental chemistry

Clinical laboratory method optimization